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MZO-005 Solved Assignment 2026 Available
Assignment Code: MZO-005/TMA/2026
Attempt all questions. The marks for each question are indicated against it.
1.a). Describe the steps of genome data analysis.
b). Write a note on Yeast Artificial Chromosome
2.a). Distinguish between temporal and site-specific analyses of gene expression.
b). Outline the technique of Isotope Coded Affinity Tag.
3.a). Elucidate the different techniques of western blotting.
b) Distinguish between Matrix Assisted Laser Desorption Ionization and Electrospray lonization.
a). Write a brief note on MALDI-TOF-TOF mass spectrometry.
b). How would you prepare a microarray?
5. a). Explain Whole Genome Shotgun Sequencing Methods with diagram.
b). Write a note on Multiple Sequence Alignment
6.a). Explain the technique of nuclear run-on assay with diagram.
b). Outline the principle of cDNA-AFLP with diagram.
7. Give a broad overview of the protein mining strategy. What is affinity chromatography?
8 Write a note on the principle and methodology of RNA Sequencing with diagram. Explain Cot curve analysis.
9. Discuss the genome organization of Drosophila and mammals. Mention the characteristics of microsatellites.
10. Write notes on:
a). Structure of globin genes
b). Pseudogenes



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